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Pfizer begins testing omicron-matched COVID shots in adults

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Pfizer begins testing omicron-matched COVID shots in adults

By LAURAN NEERGAARD

Pfizer is enrolling healthy adults to test a reformulated COVID-19 vaccine that matches the hugely contagious omicron variant, to see how it compares with the original shots.

Pfizer and its partner BioNTech announced the study on Tuesday.

COVID-19 vaccine-makers have been updating their shots to better match omicron in case global health authorities decide the change is needed.

Omicron is more likely than previous variants to cause infection even in people who’ve been vaccinated, but it’s not yet clear that a change to the vaccine recipe will be ordered. Among the issues regulators are weighing: Some of the first places to face an omicron surge already are seeing the mutant wane — and there’s no way to know if the next variant that arises will resemble omicron or be totally different.

The original vaccines still offer good protection against severe illness and death. Studies in the U.S. and elsewhere have made clear that adding a booster dose strengthens that protection and improves the chances of avoiding even a milder infection.

“We recognize the need to be prepared in the event this protection wanes over time and to potentially help address omicron and new variants in the future,” Kathrin Jansen, Pfizer’s vaccine research chief, said in a statement.

The new U.S. study will include up to 1,420 volunteers ages 18 to 55 to test the updated omicron-based shots for use as a booster or for primary vaccinations. Researchers will examine the tweaked vaccine’s safety and how it revs up the immune system in comparison to the original shots.

Full study results will take many months as volunteers receive multiple vaccine doses — and as researchers measure how long virus-fighting antibodies remain at high levels after an omicron-adapted dose versus the regular booster.

Pfizer’s CEO told CNBC earlier this month that the company could have some omicron-matched doses ready as early as March. But doing what the company calls “at-risk” manufacturing doesn’t mean those doses will be rolled out to the public. Pfizer and other vaccine makers also have brewed and tested experimental doses to match previous variants, changes that ultimately weren’t needed but offered valuable practice at tweaking the recipe.

For the new study, one group of about 600 volunteers who received two doses of the current Pfizer vaccine three to six months ago will receive either one or two omicron-based shots as boosters. Another 600 who have already gotten three regular doses of the Pfizer vaccine will be given a fourth dose of either the regular vaccine or the omicron-matched version.

The study also will enroll some unvaccinated volunteers who will receive three doses of the omicron-based vaccine.

Pfizer plans to produce 4 billion vaccine doses in 2022, and said Tuesday the amount isn’t expected to change if an omicron-adapted version is needed.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

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FBI Most Wanted Season 3 Episode 22: May 24 Release, Time And Plot Speculations

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FBI Most Wanted Season 3 Episode 22: May 24 Release, Time And Plot Speculations

FBI Most Wanted is a famous American detective drama television program that premiered on January 7, 2020. René Balcer conceived this tv show, which has been produced by Wolf Entertainment. After only a few episodes, the sitcom became so popular that it was renewed for a second season.

CBS extended the sitcom for season 3 in March 2021, which will be broadcast on September 21, 2021. The majority of the episodes of FBI Most Wanted Season 3 have already aired. The viewers are amazed by this program and are desperate to learn when the next episode, FBI Most Wanted Season 3 Episode 22, will be released. If you are also waiting then, you’ve come to the perfect spot. On this page, we have updated all of the information regarding FBI Most Wanted Season 3 Episode 22.

What is the Story About?

“The plot primarily revolves around the FBI’s Fugitive Task Force, a small and unorthodox squad designed to track down and apprehend infamous individuals on the Bureau’s Most Wanted List.” The research team is led by Supervisory Special Agent Jess LaCroix, who is also a crime analyst and adept stalker. Special Investigator Sheryl Barnes, a former investigator with a background in behavioral science and the group’s second in leadership, is an Army veteran, and a technology genius. Other group members include the squad’s intelligence specialist, Special Agent Clinton Skye, a highly skilled sharpshooter with a law background and one of LaCroix’s most accomplished operatives, and his brother-in-law.”

When will FBI Most Wanted Season 3 Episode 22 Be Released? And What is its Plot Speculation

The next episode is called “A Man Without a Country.” The episode would premiere on CBS on May 24, 2022, at 10 p.m. ET. It is also available to watch online. The show portrays the crew as they pursue an oligarch who embarks on a horror rampage to leave an untenable position.

Where to watch FBI Most Wanted Season 3 Episode 22?

1653406962 916 FBI Most Wanted Season 3 Episode 22 May 24 Release

The upcoming episode of FBI: Most Wanted Season 3 would run on CBS the following Tuesday at 10:00 p.m. ET. Paramount+ allows you to view episodes streaming. You may also follow the series live on CBS’s online site. FBI: MW season 3 episodes premiere once a week on the channel and digitally.

There is also a plethora of different viewing and VOD services where you may enjoy the series digitally. Season 3 is now available for viewing on Paramount Plus, Spectrum On-Demand, Paramount+ Amazon Channel, and Pluto TV for free with advertisements. Season 3 are also available on Apple iTunes, Microsoft Store, Vudu, Amazon Video, and Google Play Movies.

Recap of FBI Most Wanted Season 3 Episode 21

In the FBI: Most Wanted Season 3 Episode 21, the teacher told her customer about the school. Along with this, she cleared up the financial difficulties building following an in-home yoga lesson. The teacher granted a loan by his wife. On that day, the pair arrived at the instructor’s house and demanded the funds refunded. The instructor returned the payment and inquired as to why her spouse mentioned a school from her background. Then she brutally slaughtered them!

The post FBI Most Wanted Season 3 Episode 22: May 24 Release, Time And Plot Speculations appeared first on Gizmo Story.

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JKSSB Driving Test notice for various posts

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JKSSB Driving Test notice for various posts

JKSSB Driving Test notice for various posts

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Also Read : JKSSB Junior Statistical Assistant Final Selection list PDF

Also Read : JKSSB Releases Selection Lists for Various Posts, Check here

JKSSB Driving Test notice for various posts

The post JKSSB Driving Test notice for various posts appeared first on JK Breaking News.

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Ex-White House press secretary Jen Psaki hired by MSNBC

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Ex-White House press secretary Jen Psaki hired by MSNBC

By MARK KENNEDY

NEW YORK (AP) — Former White House press secretary Jen Psaki has officially landed at MSNBC, where she is expected to make appearances on the network’s cable and streaming programs as well as host a new original show.

The program, set to debut in the first quarter of 2023, will “bring together her unique perspective from behind the podium and her deep experience in the highest levels of government and presidential politics,” the network said in a statement Tuesday.

Psaki will also appear on NBC and during MSNBC’s primetime special election programming throughout the midterms and 2024 presidential election.

Psaki most recently served as White House spokesperson for the first 16 months of the Biden administration. She previously served as White House communications director under former President Barack Obama and as the spokeswoman for the Department of State.

“Her extensive experience in government and on the campaign trail and perspective as a White House and Washington insider is the type of analysis that sets MSNBC apart,” MSNBC President Rashida Jones said in a statement. “She’s a familiar face and trusted authority to MSNBC viewers, and we look forward to her insight during this consequential election season.”

At MSNBC, on-air personalities are mostly sympathetic to Biden and the Democrats. During Psaki’s White House tenure, Democrats saw her as a champion of their causes, while conservatives found her combative and standoffish.

MSNBC has also hired Symone Sanders, former chief spokeswoman for Vice President Kamala Harris. NBC News has taken pains to draw distinctions between its journalists and MSNBC, which has beefed up its opinion programming.

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