A remark Barbra Streisand left on an Instagram submit shared by Melissa McCarthy this week has sparked a dialog about weight, shaming and the more and more widespread use of medication for weight reduction.

McCarthy, 53, shared two images on her Instagram web page Sunday of herself with director Adam Shankman attending a gala in Los Angeles over the weekend.

Within the feedback part, Streisand, 82, responded to McCarthy’s images, writing, “Give him my regards,” referring to Shankman, earlier than including, “did you’re taking Ozempic?”

Streisand’s remark, which has since been deleted, was captured by the Instagram account Feedback by Celebs, which posted a screengrab of the remark by itself Instagram web page, writing, “Babs!!”

In a follow-up submit on her Instagram story hours later, Streisand addressed the remark publicly, writing, “OMG – I went on Instagram to see the images we would posted of the gorgeous flowers I might obtained for my birthday! Beneath them was a photograph of my good friend Melissa McCarthy who I sang with on my Encore album. She appeared improbable! I simply wished to pay her a praise. I forgot the world is studying!”

McCarthy and Streisand have labored collectively prior to now, together with performing a duet in 2016.

Late Tuesday, McCarthy responded with an Instagram submit of her personal, saying in a video, “The takeaway? Barbra Streisand is aware of I exist. She reached out to me and she or he thought I appeared good. I win the day.”

The video, during which McCarthy was seen holding {a magazine} that includes Streisand, was captioned with the phrases, “@barbrastreisand fan membership members solely!!!” adopted by 4 coronary heart emojis.

Is it ever OK to ask an individual about their weight?

Streisand’s remark, which was left from her verified Instagram account, shortly led to a debate on social media in regards to the shaming round medicine used for weight reduction, together with Ozempic.

“Why is it that individuals that have not had weight problems care a lot – what does it matter Barbara? If she has or hasn’t it isn’t your concern,” wrote one commenter, including, “and even when it was meant to be a DM – nonetheless impolite!”

“Ozempic admit or preserve silent!!” wrote one other commenter. “Not one movie star has admitted to shedding over the magic variety of 40 kilos in each article written all over the world. Nobody needs to confess they’ve been on the med for a yr and have dropped 6 sizes and making an attempt to elucidate away solely 40 kilos. Whole nonsense.”

Over the previous two years, medicines that may result in weight reduction, together with Ozempic in addition to Zepbound, Wegovy and Mounjaro, have change into extra broadly obtainable and have skyrocketed in recognition.

Each Ozempic and Mounjaro are authorised by the U.S. Meals and Drug Administration to deal with Kind 2 diabetes, however some docs prescribe the remedy “off-label” for weight reduction, as is permissible by the FDA.

Wegovy and Zepbound, which comprise the identical energetic substances as Ozempic and Mounjaro, respectively, are every FDA-approved as a weight reduction administration remedy for folks with weight problems, or those that are obese with at the very least one associated underlying situation, akin to hypertension.

Because the panorama of weight problems medication has modified over the previous two years, the general public notion of weight problems as a power medical situation has seemingly struggled to maintain tempo.

Individuals who take medicines for weight reduction, together with Oprah Winfrey, have spoken publicly about feeling shamed for taking what some have labeled “the simple method out” for weight reduction.

“The truth that there is a medically authorised prescription for managing weight and staying more healthy, in my lifetime, appears like reduction, like redemption, like a present, and never one thing to cover behind and as soon as once more be ridiculed for,” Winfrey mentioned when she first publicly confirmed she was utilizing a drugs to assist preserve her weight.

Whereas McCarthy has spoken publicly prior to now about her weight journey and her experiences with physique shaming, she shouldn’t be identified to have spoken publicly about Ozempic or different medicines for weight reduction.

In a 2016 interview, the “Bridesmaids” actress mentioned she by no means needs weight to be “essentially the most attention-grabbing factor” about herself.

“I will be up, I will be down, in all probability for the remainder of my life,” she informed Refinery29 of her weight. “The factor is, if that’s the most attention-grabbing factor about me, I have to go have a lavender farm in Minnesota and provides this up.”

McCarthy continued, “There must be one thing extra. There are such a lot of extra intriguing issues about ladies than their butt or their this or their that. It might’t be the primary query each time, or a query in any respect.”

What docs say about weight and shaming

That the subject of weight continues to carry such a grip on society possible stems from the truth that it’s each so common and so seen, in that individuals can see weight reduction or weight achieve, weight problems medication specialists say.

Weight problems is a medical situation that impacts practically 42% of individuals within the U.S., in keeping with the U.S. Facilities for Illness Management and Prevention. Weight problems has been related to situations like stroke and coronary heart assault, hypertension, respiration difficulties, sleep apnea and an elevated threat of early demise.

“The truth is that, sure, weight problems is a illness, however not like different ailments, you possibly can see it. That is a part of the difficulty,” Dr. Caroline Apovian, an endocrinologist and co-director of the Middle for Weight Administration and Wellness at Brigham and Girls’s Hospital in Boston, informed ABC Information. “And its not a illness that impacts 1 in one million. It impacts 42% of grownup Individuals.”

Apovian mentioned the truth that weight problems impacts so many individuals could make it appear extra approachable to speak about, although it’s a medical situation that affords privateness.

“There are various people who find themselves well-known who discuss their battles with breast most cancers or ovarian most cancers or coronary heart illness and weight problems,” she mentioned. “However on this occasion, there’s a nuance right here, since you would by no means have thought to touch upon a photograph of someone and say, ‘Hey, I see you do not have breast most cancers. Did you’re taking chemo?'”

Dr. Fatima Cody Stanford, an weight problems medication doctor scientist and educator at Massachusetts Common Hospital and Harvard Medical College, echoed Apovian’s feedback on weight problems being a “seen” medical situation.

Stanford argues it isn’t “honest” for folks to ask questions or make judgment calls on how a person treats their medical situation, even whether it is one the general public can see.

“We should not have the ability to make a judgment name on how an individual has chosen to handle this illness, whether or not they’ve chosen way of life or behavioral modifications, whether or not they’ve chosen medicines or whether or not they’ve chosen metabolic or bariatric surgical procedure or, for a lot of of my sufferers, all the above,” Stanford informed ABC Information. “People which have chosen these methods do not owe anybody an evidence on how or why or once they’ve chosen to make use of the methods to handle their power illness of weight problems.”

Stanford mentioned a few of society’s acceptance with speaking about folks’s weight could should do with misconceptions in regards to the situation of weight problems, which she describes as a power, relapse-remitting illness that could be a results of an individual’s genetic make-up.

In the identical method, medicines used for weight reduction are sometimes mischaracterized because the “straightforward method out” as a result of they could be misunderstood, in keeping with Stanford.

The medicines work by mimicking a hormone, glucagon-like peptide-1, generally known as GLP-1, that’s made by the small gut and helps ship satiety alerts within the physique.

The energetic ingredient in Mounjaro and Zepbound, tirzepatide, works by activating two hormone receptors: GLP-1 and glucose-dependent insulinotropic polypeptide, or GIP.

In Ozempic and Wegovy, the energetic ingredient, semaglutide, works by activating solely the GLP-1 receptor.

“I feel lots of people don’t know that each single human who was ever born and lived has GLP-1s of their physique,” Stanford mentioned. “These of us that occur to have a leaner physique as a baseline simply occur to have extra GLP-1 at baseline. These of us who simply weren’t born with that privilege occur to want extra of this, and possibly get it by the type of a drugs.”

Stanford mentioned it’s flawed to criticize or query individuals who use medicines for weight reduction as a result of that’s blaming them for his or her “physiology having some dysfunction.”

“I do not care for those who’re a star or a mean affected person and not using a movie star standing, I do not assume we should always choose folks for what they’re or aren’t taking,” Stanford mentioned. “A few of us do not have the identical privilege as others to have a completely functioning physique, so let’s give the others a good shot.”