Oppenheimer Upgrades Vertex Pharmaceuticals (VRTX)

Fintel reports that on February 13, 2026, Oppenheimer upgraded their outlook for Vertex Pharmaceuticals (NasdaqGS:VRTX) from Perform to Outperform.

Analyst Price Forecast Suggests 14.51% Upside

As of February 4, 2026, the average one-year price target for Vertex Pharmaceuticals is $532.50/share. The forecasts range from a low of $360.99 to a high of $656.25. The average price target represents an increase of 14.51% from its latest reported closing price of $465.02 / share.

See our leaderboard of companies with the largest price target upside.

The projected annual revenue for Vertex Pharmaceuticals is 10,721MM, a decrease of 10.67%. The projected annual non-GAAP EPS is 19.52.

What is the Fund Sentiment?

There are 2,463 funds or institutions reporting positions in Vertex Pharmaceuticals. This is an decrease of 214 owner(s) or 7.99% in the last quarter. Average portfolio weight of all funds dedicated to VRTX is 0.36%, an increase of 9.63%. Total shares owned by institutions decreased in the last three months by 8.10% to 281,598K shares. The put/call ratio of VRTX is 0.87, indicating a bullish outlook.

What are Other Shareholders Doing?

Capital World Investors holds 25,510K shares representing 10.05% ownership of the company. In its prior filing, the firm reported owning 25,911K shares , representing a decrease of 1.57%. The firm increased its portfolio allocation in VRTX by 13.46% over the last quarter.

Capital Research Global Investors holds 17,316K shares representing 6.83% ownership of the company. In its prior filing, the firm reported owning 16,553K shares , representing an increase of 4.41%. The firm increased its portfolio allocation in VRTX by 19.14% over the last quarter.

VTSMX – Vanguard Total Stock Market Index Fund Investor Shares holds 8,262K shares representing 3.26% ownership of the company. In its prior filing, the firm reported owning 8,112K shares , representing an increase of 1.82%. The firm decreased its portfolio allocation in VRTX by 16.55% over the last quarter.

VFINX – Vanguard 500 Index Fund Investor Shares holds 7,289K shares representing 2.87% ownership of the company. In its prior filing, the firm reported owning 7,134K shares , representing an increase of 2.12%. The firm decreased its portfolio allocation in VRTX by 16.65% over the last quarter.

Jpmorgan Chase holds 6,039K shares representing 2.38% ownership of the company. In its prior filing, the firm reported owning 6,435K shares , representing a decrease of 6.55%. The firm decreased its portfolio allocation in VRTX by 87.54% over the last quarter.

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This story originally appeared on Fintel.

The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

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