Cruz Azul vs Santos Laguna Predictions
Main Match Prediction
Santos Asian Hcp +1.25 @ -106
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Bet on the Underdogs to Cover the Line
We can bank some insurance on the outsiders by wagering Santos Laguna +1.25 at -106 on the Asian Handicap. Our money is divided between +1 and +1.5 and we’re happy to back them against Cruz Azul.
Explore our full Cruz Azul vs Santos Laguna betting preview, which features the complete write-up for our main match prediction, alongside our correct score prediction, player prop picks, corners prediction and bet builder tips.
Cruz Azul vs Santos Laguna Preview
Cruz Azul go head-to-head with Santos Laguna at Estadio Banorte, with kick-off set for 19:00 on Sunday 6 September.
Cruz Azul have been handed two Liga MX home losses in a row. In their last league game, they beat Club Necaxa away by a 3-1 scoreline at Estadio Victoria. Joel Huiqui’s team enjoyed 54% possession and had eight shots on target, while Jeremy Marquez, Nicolas Ibanez and Willer Ditta scored one goal each.
Santos Laguna drew 0-0 against Tigres UANL in their previous game. This was on home soil at Estadio Nuevo Corona. The Comarca Lagunera outfit had the lion’s share of the ball boasting 59% possession and three shots on goal.
2-1 Win for Cruz Azul in Last H2H Battle
Cruz Azul have beaten Santos on four consecutive occasions. Their last clash saw Cruz Azul enjoy a 2-1 away win at Estadio Nuevo Corona. The previous 10 H2H meetings have involved five Cruz Azul wins, three Santos victories and two draws.
Cruz Azul – Last 10 League Games
Cruz Azul have 5 wins, 3 losses and 2 draws, averaging 1.7 goals from 6.0 shots on goal and 12.7 attempts. La Máquina Celeste have averaged 47.6% possession and 6.0 corners per game, with the opposition getting 1.5 goals from 3.7 shots on goal, 8.3 attempts and 4.3 corners.
Players to Watch
Top scorer Jeremy Marquez has found the net 4 times, Nicolas Ibanez 3, with Agustin Palavecino and Christian Ebere both scoring 2. Leading assistor is Carlos Rodriguez with 5.
Santos Laguna – Last 10 League Games
Santos have won 1, lost 8 and drawn 1, averaging 8.3 attempts, 2.5 shots on goal and 0.9 goals. Renato Paiva’s side average 50.4% possession, 5.9 corners in their favour and 5.1 corners against, while 1.8 goals have been conceded from 5.8 shots on goal and 12.6 attempts.
Players to Watch
Lucas Di Yorio has scored 3 goals, followed by Ezequiel Bullaude, Eduardo Aguirre, Emmanuel Echeverria and Aldo Lopez on 1. Ezequiel Bullaude has managed to clock up 3 assists in the last 10 games.
Confirmed Lineups
Cruz Azul confirmed lineup (5-3-2): Kevin Mier (GK), Willer Ditta, Amaury Garcia, Jesus Orozco, Jeremy Marquez, Omar Campos, Agustin Palavecino, Rogelio Gonzalez, Carlos Rodriguez, Nicolas Ibanez, Luka Romero.
Santos Laguna confirmed lineup (4-2-3-1): Carlos Acevedo (GK), Mauricio Cuevas, Jonathan Perez Sanchez, Felipe Sanchez, Efrain Orona, Salvador Mariscal, Aldo Lopez, Diego Gonzalez, Luis Gomez, Kevin Palacios, Ezequiel Bullaude.
Main Match Prediction
We can’t pass up the chance to wager Santos Laguna +1.25 on the Asian Handicap. Take the price of -106 for this Liga MX match in the expectation that the underdogs can run their opponents close.
Key stats supporting our main match prediction (league matches):
Getting the lowdown on injuries and studying the Liga MX form guide are important duties ahead of making football predictions. We also place great emphasis on the stats and a data-led approach can sometimes be effective.
Santos +1.25 Probability
The betting odds at the top bookies suggest our pick carries a 51.5% chance of winning. Based on our experts research, we calculate the actual probability to be closer to 60%. That means we’re regarding it as a value bet.
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Published 01:27, 05 September 2026
Player Prop Picks
Fran Villalba (Santos) can be wagered to register at least one shot on goal at +145. We’ll take a chance with this Shots on Target pick as the betting odds look pretty attractive.
Latest Fran Villalba Player Prop Odds
Goalscorer
Shots On Target
Ezequiel Bullaude (Santos) has registered three goals in his past nine Liga MX matches away from home. We think there’s value in backing him for an Anytime Goalscorer prop bet at +370 which will hopefully see him find the net.
Latest Ezequiel Bullaude Player Prop Odds
Goalscorer
Shots On Target
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Corners Prediction
The 3.5 corners line has been covered by Santos in six consecutive matches, with Cruz Azul conceding over 3.5 corners in their past four games. There’s an opportunity to go over the Santos Team Corners line and we’re expecting this to happen, with odds of -102 available.
League Games
Cruz Azul
Total
10.30
6.00
4.30
Home
8.90
6.10
2.80
Away
11.30
6.10
5.20
Santos
Total
11.00
5.90
5.10
Home
10.10
5.40
4.70
Away
9.70
5.10
4.60
Latest Corner Odds
Total Corners
Cruz Azul Corners
Santos Corners
Most Corners
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Cruz Azul vs Santos Laguna Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Cruz Azul Victory on the Cards According to Betting Sites
The bookmakers take few chances with their latest odds of -303 for Cruz Azul winning which suggests that they have a 75% chance in this Liga MX encounter. If you want to wager on the underdog, Santos Laguna have been priced up at +650.
You can take advantage of the Half-Time Result market if you think a team will lead at the break. There’s the chance to back Cruz Azul at -149, go for Santos at +480 or take the draw at +170.
There’s a high probability that Over 2.5 Goals will be netted according to the current prices. For those expecting both sides to find the net, Both Teams to Score Yes is available at -172.
The best football betting sites have excellent coverage for the latest Liga MX games. They supply customers with hundreds of markets and it’s down to you to find the best angle.
Full-Time Result
Half-Time Result
Double Chance
Draw No Bet
Asian Handicap
Total Goals
Both Teams to Score
Gabriel Matías Fernández Favourite to Find the Net First
Those interested in favourite Gabriel Matías Fernández to find the net first are able to get +310. If the Anytime Goalscorer angle makes more appeal, then this is -114.
Player Goals
Gabriel Matías Fernández (Cruz Azul)
Christian Ebere (Cruz Azul)
Nicolás Ibañez (Cruz Azul)
Agustin Palavecino (Cruz Azul)
Player Shots On Target
Nicolás Ibañez (Cruz Azul)
Agustin Palavecino (Cruz Azul)
Lucas Di Yorio (Santos)
José Paradela (Cruz Azul)
Live market odds and lines updated regularly. All odds subject to change. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Estadio Banorte
Cruz Azul Have Avoided Defeat in Past Three H2H Estadio Banorte Games
Stats: Liga MX matches only
Cruz Azul have clocked up four wins, three draws and three defeats in the past 10 home games, recording an average of 1.60 goals per match and conceding 1.20.
The past six Santos Laguna games on the road have ended in defeat. The Comarca Lagunera outfit have finished with eight defeats, one win and one draw in the past 10 away matches, netting an average of 1.20 goals per game and conceding 2.80.
Cruz Azul won 3-2 when they last played Santos at Estadio Banorte. It’s been four Cruz Azul wins, two draws and two Santos victories in the past 8 H2H meetings at Estadio Banorte.
 Cruz Azul Home Stats |
4-3-3 | 2.80 | 1.60 | 1.20 | 6 | 4 | 6 | 4 | |
 Santos Laguna Away Stats |
1-1-8 | 4.00 | 1.20 | 2.80 | 9 | 1 | 7 | 3 | |
- W-D-L = Wins-Draws-Losses
- G = Avg. Goals
- GF = Avg. Goals For
- GA = Avg. Goals Against
- O2.5 = Matches Over 2.5 Goals
- U2.5 = Matches Under 2.5 Goals
- B-Y = Matches BTTS Yes
- B-No = Matches BTTS No
Cruz Azul vs Santos Laguna Lineups & Team News
Don’t miss the latest Cruz Azul vs Santos team news before you bet. We’ll share both predicted and confirmed lineups for the Liga MX along with the latest injury news.
Cruz Azul Confirmed Lineup 5-3-2
Santos Laguna Confirmed Lineup 4-2-3-1
Cruz Azul Confirmed Lineup 5-3-2
23
Kevin Mier
4
Willer Ditta
17
Amaury Garcia
5
Jesus Orozco
16
Jeremy Marquez
3
Omar Campos
8
Agustin Palavecino
55
Rogelio Gonzalez
19
Carlos Rodriguez
7
Nicolas Ibanez
18
Luka Romero
1
Carlos Acevedo
3
Mauricio Cuevas
28
J. Perez Sanchez
25
Felipe Sanchez
14
Efrain Orona
8
Salvador Mariscal
5
Aldo Lopez
7
Diego Gonzalez
193
Luis Gomez
77
Kevin Palacios
10
Ezequiel Bullaude
Santos Laguna Confirmed Lineup 4-2-3-1
Cruz Azul Substitutes
- 1Andres Gudino
- 2Alan Mozo
- 6Erik Lira
- 10Andres Montano
- 11Christian Ebere
- 12Alan Montes
- 20Jose Paradela
- 21Gabriel Fernandez
- 22Jorge Rodarte
- 33Gonzalo Piovi
Santos Laguna Substitutes
- 4Jose Abella
- 6Javier Guemez
- 17Emmanuel Echeverria
- 18Franco Pardo
- 19Eduardo Aguirre
- 20Esteban Lozano
- 21Fran Villalba
- 24Diego Medina
- 26Ramiro Sordo
- 33Hector Holguin
Previous Cruz Azul Lineups
28 Aug
Liga MX
Necaxa
1-3
Cruz Azul
22 Aug
Liga MX
Cruz Azul
0-2
Atlas
16 Aug
Liga MX
Tijuana
2-1
Cruz Azul
01 Aug
Liga MX
Cruz Azul
2-3
Atlante
25 Jul
Supercopa de la Liga MX
Toluca
1-3
Cruz Azul
21 Jul
Liga MX
Cruz Azul
2-1
Puebla
Previous Santos Laguna Lineups
29 Aug
Liga MX
Santos Laguna
0-0
Tigres
22 Aug
Liga MX
Puebla
3-2
Santos Laguna
16 Aug
Liga MX
Santos Laguna
0-1
Guadalajara
02 Aug
Liga MX
América
3-0
Santos Laguna
25 Jul
Liga MX
Santos Laguna
0-1
Atlas
18 Jul
Liga MX
Monterrey
3-2
Santos Laguna
Expert Analysis by Diego Sánchez
Liga MX Analyst
About the Analyst
Our football previews are produced by a specialised team of analysts, former odds compilers and sports journalists. Picks are research-driven and reviewed for accuracy and editorial consistency under the oversight of our Football Editorial Betting Panel and Editor-in-Chief.
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Liga MX Predictions Methodology
Our Liga MX analysis blends squad rotation, home altitude advantage and card/suspension trends with odds movement across both the Apertura and Clausura tournaments. We use metrics such as xG, xT and defensive efficiency indicators to assess true team strength and identify value in Mexican top-flight football.
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Transparency & Safety
This preview was last updated on Sep 6, 18:00 to reflect the latest team news, injury reports, predicted and confirmed lineups, advanced performance metrics and market movement.
All analysis is produced by professional analysts, supported by proprietary internal models, advanced performance metrics and reviewed by our Football Betting Panel for accuracy and consistency.
Historical performance for our main match predictions is tracked and updated regularly for transparency.
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